Searchable, peer-reviewed, open-access proceedings from bioscience and biomedical conferences

bp0001redr6 | (1) | REDR1980

The effect of intrauterine gonadectomy on fetal and neonatal gonadotrophin secretion in the lamb

Bremner WJ , Cumming IA , Williams DM , de Kretser DM , Lee VWK

Summary. In Exp. 1, sheep fetuses (2 male and 3 female) were gonadectomized between Days 70 and 120 of gestation and their blood LH and FSH levels were compared to those of control animals (4 male, 6 female) at regular times during the first year after birth. In Exp. 2. fetuses (3 male and 5 female) were gonadectomized between Days 50 and 60 of gestation and gonadotrophin levels at Day 90 of gestation were compared to those of control fetuses of the same age. ...

bp0001redr11 | (1) | REDR1980

Effects of LH-RH infusion, castration and cryptorchidism on gonadotrophin and testosterone secretion in developing rams

Lee VWK , Bremner WJ , Cumming IA , de Kretser DM , Findlay JK

Summary. The relationship between the pituitary gland and testis in rams was studied from birth to sexual maturity. The concentrations of LH, FSH and testosterone increased between 5 and 7 weeks of age; the rise was not correlated with any specific cytological change in the testis. An augmented pituitary response to LH-RH was demonstrated as levels of gonadotrophin increased. It is unclear whether this change in sensitivity plays a role in initiation of the pu...